Tuesday, January 31, 2012

Emboldened GOP turns attention to seemingly improbable prize: eliminating state income taxes (Star Tribune)

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Giggle Launches All-in-One Baby Registry App

Giggle launches new, easy-to-use baby registry app.

Source: http://feeds.celebritybabies.com/~r/celebrity-babies/~3/mbkttCslGh4/

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S&P 500 Week in Review: Netflix Draws Investing Demand, E-Trade ...

By Scott Gillette
Scottrade: $7 Online Trades. Real-Time Stock Quotes

Monday

Netflix (NASDAQ:NFLX) was hit hard pre-market by Wedbush?s lack of confidence. Wedbush believes that Q1 earnings will be poor, and 2012 consensus estimates ill drop a buck a share. Piper Jaffray, for what it?s worth, is optimistic about Netflix, as they think the customer base will stabilize and ultimately grow again.

Don?t Miss: Netflix?s Streaming Service Comes Up Short for Movie Buffs.

Halliburton?s?(NYSE:HAL) results came in this morning, and although EPS and revenues beat estimates, the higher expectations of the market were not met. Interesting tidbit: unconventional oil drilling has twice as much activity as unconventional gas drilling.

Amgen (NASDAQ:AMGN): The entire pharmaceutical sector is being downgraded, and Amgen is no exception. Its stock has been downgraded to underweight by JP Morgan.

Earnings Report: PetMed Express Inc. Earnings: Shrinking Margins for Fifth Consecutive Quarter, Net Income Falls.

Sears Holdings Corporation (NASDAQ:SHLD): The performance of this stock has been remarkable: up 69% year to date, the stock jumped by 8% before coming down close to where it started at the beginning of trading. Some believe Sears is now in a classic short squeeze.

Southwestern Energy Co. (NYSE:SWN) popped along with other natural gas producers because the spike of prices and Chesapeake?s planned cuts in production.

Chesapeake Energy Corporation (NYSE:CHK): After sinking overnight to $2.20, natural gas futures jumped 6.4% in a matter of minutes. Apparently there were too many short-sellers in the natural gas market, and the market has taken care of them for the time being.

Tuesday

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Source: http://wallstcheatsheet.com/stocks/sp-500-week-in-review-netflix-draws-investing-demand-e-trade-under-pressure.html/

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Monday, January 30, 2012

Kelli Gail: Thank You James Dolan and Time Warner

I'd like to thank James Dolan, his evil empire and Time Warner Cable. As a New Yorker for fifteen years, this was the year I was going to become a full time Knicks fan. I was fully prepared to commit myself to watching as many games as I could. The team was poised to build upon their first-round playoff exit last season. I couldn't wait to watch the Speedball offense, the Broadway Bigs (Melo, Chandler, Amare) and B-Diddy (the combo of Baron Davis/Mike Bibby at the point) gel as a team and bring back fireworks to Madison Square Garden. I downloaded and studied the new schedule, ready to immerse myself in all things Knickerbockers. I was all in.

Then WW3 broke out between the MSG Network and Time Warner Cable over a fee dispute of a proposed whopping 53 percent fare hike for MSG subscribers. Unfortunately my building is not wired for Verizon FIOS so, along with 2.8 million other people, I now live in a perpetual Rangers and Knicks blackout. To paraphrase the Soup Nazi from Seinfeld: No Knicks for You!

Forced to get my b-ball fix from another source, I discovered that the NBA TV Network had taken the place of MSG Network on Channel 27. Thinking I would just watch for a few minutes then continue channel surfing, I was surprised when a close Cavs/Heat game pulled me in. Another night, it was a battle for LA with a Clippers vs. Lakers game. Next a magically exciting Memphis/Clips game appeared. I was hooked.

Previously a helicopter NBA playoff fan I rarely watched many games in the regular season. I usually only swooned over the superstars that littered the TV during the playoffs -- Paul Pierce, Pau Gasol, Kobe, Dirk, Dwight Howard, LeBron, D-Wade. These were the players I knew of, had seen play and rooted for.

Given the Knicks 7-13 record, James Dolan and company are actually doing me a favor. I didn't have to watch the one point Melo game or the dismal shooting performances of Iman Shumpert or Toney Douglas. I've been spared wincing through the club's attempt at playing big league defense.

Now that I have succumbed to my sports fanaticism and started watching regular season games, I have discovered many new players from the flyover states. Who knew the Grizzlies had a player on the team from Iran? Or that Kevin Love (who??) was deserving of a $60 million contract extension with Minnesota?

It's a whole new brave world out there outside of the big city. Here are five observations and questions:

1. The Memphis Grizzlies new uniforms are yellow on top and green on the bottom. Is that allowed in the Haus of David Stern? Was he too busy blocking the CP3 trade to the Lakers when someone green-lighted the unis?

2. How magnificent is the new look Clippers? I want to Occupy Lob City

3. The NBA discovered the Internet!??! Pop-up tweets pepper the screen in the down times during a game from people like Ernie Johnson in the studio or Doc Rivers' son who begged his dad to put him into the lineup when the team was losing. Does this mean the players will now be allowed to tweet during half-time or time-outs?

4. TNT has a new American Idol-Style stage where Kenny the Jet can excitedly bounce around in front of and review plays of game tape. I have a request: Can he sing 'Benny and the Jets', or 'Everyone Wang Chung Tonight' up there? I'm good with either.

5. One thing that hasn't changed: Craig Sager still has the market cornered on the ugliest blazers in the history of television

I owe a debt of gratitude to all the greedy people who wanted to exponentially up the carriage
charges for us poor suckers to watch the hometown team. If they had come to an agreement to
force me to pay more for a bad product, I would not have discovered there is life outside of the Big Apple when it comes to sports. Shhh, just don't tell Giants fans that.

?

Follow Kelli Gail on Twitter: www.twitter.com/kelligail

Source: http://www.huffingtonpost.com/kelli-gail/time-warner-msg_b_1239085.html

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Sunday, January 29, 2012

Myanmar's Suu Kyi making first campaign tour (AP)

DAWEI, Myanmar ? Opposition leader Aung San Suu Kyi made her first campaign tour for parliament Sunday in Myanmar's countryside, advancing a bid that shows how quickly and dramatically politics is changing in this long-repressed Southeast Asian nation.

Thousands of cheering supporters crowded the airport to greet Suu Kyi in the southern town of Dawei and lined the roads shouting: "Long Live Daw Aung San Suu Kyi!" "Daw" is a title of respect in Myanmar.

Many waved bouquets of flowers, and some hoisted babies on their shoulders to glimpse the Nobel Peace laureate, who is revered as Myanmar's icon for democracy. Banners with pictures of Suu Kyi decorated the town.

"People had been afraid to discuss politics for so long," said Aung Zaw Hein, an environmental activist. "Now that she's visiting, the political spirit of people has been awakened."

Suu Kyi, 66, has devoted much of her life to the struggle against authoritarian rule, but spent 15 of the past 23 years under house arrest and has never held elected office. If she wins, Suu Kyi will have limited power in the legislature, which remains dominated by the military and the ruling party, but victory would be highly symbolic and give the longtime political prisoner a voice in government for the first time.

The one-day campaign stop in Dawei follows a series of unprecedented reforms enacted by the nominally civilian government that took over when a military junta ceded power last year. The government has released hundreds of political prisoners, reached cease-fire deals with ethnic rebels, increased press freedoms and eased censorship laws.

The April 1 by-election is being held to fill 48 seats in the lower house of parliament that were vacated after lawmakers were appointed to the Cabinet and other posts last year.

Her party boycotted the last vote in 2010, but registered earlier this month for by-elections after authorities amended electoral laws, enabling her party to legally participate.

The Election Commission must still accept Suu Kyi's candidacy. A ruling is expected in February.

Suu Kyi is hoping to run for representative for the constituency of Kawhmu, a poor district just south of Yangon where villagers' livelihoods were devastated by Cyclone Nargis in 2008.

The vote is being closely watched at home and abroad because it is seen as a crucial test of the regime's commitment to change.

Suu Kyi, who won the Nobel Peace Prize in 1991 for her nonviolent struggle for democracy, has rarely traveled over the last two decades outside Yangon, the country's main city.

Although she conducted one successful day of rallies in two small towns north of Yangon last August, a previous political tour to greet supporters in 2003 sparked a bloody ambush on her convoy that saw her forcibly confined to house arrest at her lakeside home.

Suu Kyi was finally released from house arrest in late 2010, just days after the country's military rulers organized elections widely viewed as neither free nor fair.

In Dawei, a coastal town south of Yangon, Suu Kyi will campaign on behalf of another candidate running for a parliament seat, party spokesman Nyan Win said.

She will make similar campaign trips to other Burmese towns, including the country's second city, Mandalay, in early February before campaigning for her own seat, Nyan Win said.

In Dawei, Suu Kyi will meet party supporters and conduct rallies. The town is home to activists who recently helped persuade the government to ditch construction of a 4,000-megawatt coal-fired power plant over environmental concerns.

A 400-megawatt coal plant is still planned, however, because it will be needed to fuel a massive industrial complex project that includes construction of a deep sea port, a steel mill and a petrochemical plant. The project also includes railroads and highways that will connect Burma's coast directly to Thailand and the rest of Southeast Asia.

Source: http://us.rd.yahoo.com/dailynews/rss/asia/*http%3A//news.yahoo.com/s/ap/20120129/ap_on_re_as/as_myanmar_suu_kyi

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NHL commissioner: Plan B for Coyotes is premature

OTTAWA (AP) ? Price is not holding up the sale of the Phoenix Coyotes, and it's premature to discuss a Plan B for the franchise's future, according to NHL Commissioner Gary Bettman.

Speaking after the NHL's Board of Governors meeting on Saturday during the All-Star weekend in Ottawa, Bettman remained hopeful a deal can be reached with one of three prospective buyers to keep the league-controlled Coyotes in Glendale, Ariz.

"We hope, based on the things that are ongoing, to have a sale in place before the end of the season that would keep the team in Glendale," Bettman said. "I don't see any reason to discuss a Plan B at this point."

He disputed concerns raised by Glendale officials that the NHL's asking price ? believed to be around $170 million ? might be holding up the sale. Bettman said the price hasn't been an issue with any of the three groups interested in purchasing the team.

On other topics, Bettman acknowledged a longstanding rift between New Jersey Devils owners Jeff Vanderbeek and Ray Chambers. Describing the franchise as stable, Bettman said the NHL is attempting to resolve the dispute by having one or the other assume control.

As for labor talks, Bettman said he intends to open informal discussions with the NHL Players' Association soon, but adds no timetable has been set for formal talks. The current deal expires in September.

The Coyotes, however, remain the NHL's most pressing concern. The league has been operating the club for the past two seasons, with Glendale kicking in $25 million in each of the past two years to keep the team afloat.

The two groups known to have expressed interest in the Coyotes are one led by former San Jose Sharks president and CEO Greg Jamison, and another by Chicago sports mogul Jerry Reinsdorf. Without providing names, Bettman on Thursday revealed there is also a third group that's shown "serious" interest in the team.

Bettman on Saturday declined to shed any new light on the third group and who might be involved.

NHL Deputy Commissioner Bill Daly described the third group as "legitimate."

"They've been working at it for a while," Daly said. "They've been spending money, they've been doing due diligence. So those are all positive signs. It doesn't mean they're going to buy the franchise so we'll see how it plays out."

Bettman said there's no timetable for completing a sale, and the commissioner also sent a message to any North American market interested in luring the Coyotes by saying the league's not making any assurances.

"We've told anybody in any market who's asked, who doesn't have a team, 'Don't do anything on planning on having a team because we're not making anybody any promises of anything,'" Bettman said.

Bettman didn't mention what communities he was referring to, but his statement came before a large contingent of French-Canadian media and amid speculation that Quebec City might be the latest Canadian city in line to regain a franchise after the Nordiques relocated to Denver in 1995.

The Jets returned to Winnipeg last summer after relocating from Atlanta.

The dispute among the Devils' owners has been growing for more than a year, which Bettman acknowledged has resulted in "some difficult consequences in terms of the operation of the club."

Bettman said the NHL is attempting to resolve the dispute. Without being specific, Bettman also said the league might have to consider other alternatives to handling the matter.

Vanderbeek and his partners have been at odds since last year. Noting they have different visions for the team, Vanderbeek had been adamant that he would keep part of the franchise.

On the bright side, Bettman said the sale of the St. Louis Blues to prospective buyer Tom Stillman is proceeding on track. Stillman is a former Blues majority owner who has signed a purchase agreement to buy the franchise from Dave Checketts.

Bettman was optimistic the sale could be completed in "the not too distant future," but declined to provide a better timetable because it's not yet completed and also required NHL approval.

"We think it's on a timely track, so we're pretty optimistic that based on everything we're hearing, including from Tom, this should be a go," Bettman said.

As for labor talks, Bettman said the league is remaining patient in part because NHLPA executive director Donald Fehr is only entering his second year on the job and still assessing the needs of his members.

"We're ready and we have been ready, but the union has had some work to do," Bettman said. "We're being patient. I'm not concerned about the time frame."

He also announced next year's All-Star game will be held in Columbus, Ohio, on the final weekend of January.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2012-01-28-HKN-All-Star-Board-of-Governors/id-088859ed4ddf4c01b922c1e7bd97cf80

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Friday, January 27, 2012

Scientists link evolved, mutated gene module to syndromic autism

Friday, January 27, 2012

A team led by researchers at the University of California, San Diego School of Medicine reports that newly discovered mutations in an evolved assembly of genes cause Joubert syndrome, a form of syndromic autism.

The findings are published in the January 26 online issue of Science Express.

Joubert syndrome is a rare, recessive brain condition characterized by malformation or underdevelopment of the cerebellum and brainstem. The disease is due specifically to alterations in cellular primary cilia ? antenna-like structures found on most cells. The consequence is a range of distinct physical and cognitive disabilities, including poor muscle control, and mental retardation. Up to 40 percent of Joubert syndrome patients meet clinical criteria for autism, as well as other neurocognitive disorders, so it is considered a syndromic form of autism.

The cause or causes of Joubert syndrome are not well-understood. Researchers looked at mutations in the TMEM216 gene, which had previously been linked to the syndrome. However, only half of the expected Joubert syndrome patients exhibit TMEM216 gene mutations; the other half did not. Using genomic sequencing, the research team, led by Joseph G. Gleeson, MD, professor of neurosciences and pediatrics at UC San Diego, broadened their inquiry and discovered a second culprit: mutations in a neighboring gene called TMEM138.

"It is extraordinarily rare for two adjacent genes to cause the same human disease," said Gleeson. "The mystery that emerged from this was whether these two adjacent, non-duplicated genes causing indistinguishable disease have functional connections at the gene or protein level."

Through evolutionary analysis, the scientists concluded that the two TMEM genes became joined end-to-end approximately 260 million years ago, about the time some amphibians began transitioning into land-based reptiles. The connected genes evolved in tandem, becoming regulated by the same transcription factors.

"Prior to this transition, the two genes had wildly different expression levels," said Jeong Ho Lee, MD, PhD, and first author of the study. "Following this transition, they became tightly co-regulated. Moreover, we found that the two encoded proteins coordinate delivery of factors key for cilia assembly."

Gleeson said the findings suggest the human genome has evolved to take advantage of fortuitous ancestral events like gene translocations to better coordinate gene expression by assembling into specific modules. When these modules are disrupted, however, neurodevelopmental diseases may result.

###

University of California - San Diego: http://www.ucsd.edu

Thanks to University of California - San Diego for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/117123/Scientists_link_evolved__mutated_gene_module_to_syndromic_autism

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Steam community app available, access limited to beta participants for now

Android Central Android Central

If you're a PC or Mac gamer, chances are you've used Steam, Valve Software's leading digital distribution platform for games. Today sees the launch of the official Steam app for Android, a new application that gives you access to the Steam store and community features like Steam chat on-the-go. If you're big on Steam and the Steam community, this could definitely be worth a look.

It's worth clarifying that this isn't a fully-fledged Steam client for Android, so you won't be playing Portal 2 on your Galaxy Tab any time soon, unfortunately. All it lets you do is buy PC and Mac games and chat to your Steam friends.

While the app itself is freely available on the Android Market (see the link after the jump), you'll need to be part of the Steam Mobile beta group in order to use it, or you'll be rejected at the login screen. This is a little strange given that the app is openly advertised on SteamPowered.com with no mention that a beta invite is required. So keep an eye on this one, folks. All signs point to a possible public launch in the near future. If you are in the beta group, however, you'll find a handy Market link after the break.

Source: SteamPowered.com

read more



Source: http://feedproxy.google.com/~r/androidcentral/~3/ZBNzeQrjQ2M/story01.htm

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Calif. poised to vote on new 'clean car' regs

(AP) ? California is poised to vote on new rules that would require automakers to build cars and trucks by 2025 that emit about three-quarters less smog producing pollutants and also mandate that one of every seven new cars sold in the state be a zero emission or plug-in hybrid vehicle.

The California Air Resources Board will begin hearing testimony Thursday in Los Angeles on its "Advanced Clean Car" program, and is expected to continue on Friday.

The new emissions standards, which also include big cuts in greenhouse gas pollutants, would begin with new cars sold in 2015, and get increasingly more stringent until 2025. Generally, the regulations would require a 75 percent reduction in smog emissions in new cars by 2025, and a 34 percent reduction in greenhouse gas emissions over roughly the same time.

The new rules will continue the state's first-in-the-nation greenhouse gas emissions standards for cars and trucks, which went into effect in 2009. This time, the greenhouse gas reduction element of the program was designed with the federal regulators so that it will match national standards expected to be passed later this year.

"When we did the first greenhouse gas standards, it was war," said Tom Cackette, deputy director of the board, referring to legal challenges from auto dealers and business groups after the state passed the initial greenhouse gas emissions limits.

"They sued us in two federal courts. Fortunately, from our viewpoint, they lost. Over that time, with the increase in gas prices, the shake-up in the auto industry brought new management which looked at the future. Where's our future? It's not profits next quarter but how do we make a sustainable business."

California's smog emissions standards are often more strict than federal ones, which means other states often adopt them as their own.

Fourteen other states, including Washington, New Jersey, New York and Massachusetts, have adopted California's current emissions goals, which is why the new regulations could have a wide-ranging effect. Of those states, 10 have also adopted the zero-emission vehicle standards as well.

In addition to new smog and greenhouse gas emissions limits, the regulations being voted on also includes a new zero-emissions vehicle mandate. The goal is to have 1.4 million zero-emission and plug-in hybrids on California roads by 2025. But the program also looks ahead to 2050, laying groundwork for a goal of having 87 percent of the state's fleet of new vehicles fueled by electricity, hydrogen fuel cells or other clean technologies.

"This regulation is planned over a 40-year horizon, and that is extremely unusual," said board spokesman David Clegern. "But it gives us time to put the pieces in place with no surprises. The individual companies can plan for changes and develop the technology, and over the long haul, it will shift us away from reliance on petroleum."

The board's meeting comes just three days after federal regulators met in San Francisco to hear public comment on the Obama administration's national fuel economy standards, the most far-reaching in history. If passed later this year, they would require the average passenger car to reach a 54.5-mph standard by 2025.

The U.S. Environmental Protection Agency, 13 automakers, CARB and others worked together so that when the federal government passes its greenhouse gas emissions limits later this year, they will match California's and create one national standard.

Some automakers said the market for clean car technology is already spurring the technology and innovation the regulations seek to influence.

"Yes, the cars will be lighter, compact, far more fuel efficient. That's what the mandate will be. It's not enforced by the government but really by the economics of the future," said Michael Dobrin, a spokesman for Toyota.

Yet some auto dealers have argued that the government's emphasis on strict pollution controls will result in much higher prices for consumers.

Forrest McConnell, director of the National Automobile Dealers Association, testified during the federal hearing Tuesday that tightening fuel efficiency standards will result in unaffordable cars.

"We all want better fuel economy, but it is not free. By adding $3,200, if not more, to the average cost of a car, over seven million Americans will be priced out of the market, fleet turnover will be reduced, and public policy benefits will be delayed," McConnell said.

Other dealers say consumer demand for electric and hybrid vehicles is not what the board hopes it is.

The California New Car Dealers Association says hybrid vehicles, which have been marketed and sold for 13 years, only make up 2.1 percent of the national market, and 4.1 percent of California's market. They say the goal of making one of every seven new cars sold in California a zero-emission vehicle in roughly the same amount of time is unrealistic.

"Rather than setting vehicle manufacturers, new car dealers, and alternative vehicles themselves up for another predictable failure, (the board) should adjust the mandate to reflect a goal that is realistic and attainable," said Jonathan Morrison, the state dealers' association's director of legal and regulatory affairs.

The air board's research and environmental advocates dispute those cost increase estimates, and say increases in hybrid and other sales continue to rise as more cars hit the market. They argue that fuel cost savings will make up for any vehicle price increase.

"Our research shows a $1,400 to $1,900 car price increase, but over the life of the vehicles, the owners save $6,000 in reduced fuel and maintenance costs," said Clegern.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2012-01-26-California%20Clean%20Car%20Standards/id-e83d402a11f24a3aa02b4ba039fc6f84

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Thursday, January 26, 2012

Paramount Movies lets you stream UltraViolet films from the cloud, for a price

Paramount became the first studio to offer UltraViolet-based movies this week, with the launch of Paramount Movies. With this new service, users can purchase a film in either digital or physical form, and automatically store a copy of it within Paramount's cloud-based digital locker. You won't be able to download a UV film for offline viewing directly from the cloud, though you will be able to stream it to any iOS device (support for Android and Windows Phone remains unavailable, as does compatibility with most set-top boxes). It's all part of DECE's "buy once, play anywhere" ethos, though it should be noted that the studio's UV offerings are somewhat limited. At the moment, Paramount Movies boasts about 60 titles, all of which are available at comparatively steep prices: $20 for HD quality movies, and $13 for SD versions. Check it out for yourself at the source link below.

Paramount Movies lets you stream UltraViolet films from the cloud, for a price originally appeared on Engadget on Wed, 25 Jan 2012 07:02:00 EDT. Please see our terms for use of feeds.

Permalink SlashGear  |  sourceParamount Movies  | Email this | Comments

Source: http://www.engadget.com/2012/01/25/paramount-movies-lets-you-stream-ultraviolet-films-from-the-clou/

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A slim race for best original song at the Oscars (AP)

NEW YORK ? The race for the best original song Oscar is a slim one with two songs up for the honor, a first for the Academy Awards.

Sergio Mendes' "Real In Rio" from the animated adventure "Rio" will compete with Bret McKenzie's "Man or Muppet" from "The Muppets," despite having songs from a bevy of all-star musicians like Elton John, Mary J. Blige, will.i.am and Pink in contention for nomination.

Charles Bernstein, the former chairman of the Academy Awards' music branch, says he "personally was surprised" that only two songs are up for the honor.

In the past, the number of nominees for best original song has ranged from three to 14. Only up to five songs are eligible for nomination.

"I personally felt that there may have been more than two that I personally would have championed," he said in an interview after the Oscars nominations were announced Tuesday. "But it is a majority vote situation."

Blige, who co-wrote a song for the Deep South drama "The Help," said in a tweet Tuesday that she was sad, and felt like the Academy "is being mean" for only nominating two songs for the award.

This year, 39 songs were eligible for nomination for best original song, including tracks from Brad Paisley, Robbie Williams, The National, Zooey Deschanel, Zac Brown, Chris Cornell and others.

Members of the music branch can rank songs using 10, 9.5, 9, 8.5, 8, 7.5, 7, 6.5 or 6, and a song must have at least an average score of 8.25 to be nominated. If only one song gets that score, it and the song receiving the next highest score will be the two nominees.

Since two songs were nominated, it could mean that voters were unimpressed with this year's contenders.

"Each person is voting on a subjective impression ... so you'd have to go into the head of each individual voter to kind of know what it was that made them feel that any given song was or wasn't award-worthy," Bernstein said.

Bernstein also stressed that the songs "have to be written for the picture, and the judgment of its quality has a great deal to do with how it functions in the movie as well as how well written it is."

Bernstein, who did vote in the category, wouldn't say how many people voted this year, but did say that the rules for each Academy Award are carefully observed each year. He says the music branch will most likely take a closer look at the requirements for best original song after this year's results.

"It's very likely because there were two this year that the rules committee will probably take another look at it next year and make sure it wants to continue the same rules," he said.

Madonna's "Masterpiece," which won the Golden Globe for best original song and is from her directorial effort "W.E.," was not eligible for an Academy Award because "the song does not occur either in the body of the film, or as the first song at the end of the film," Bernstein said.

Mendes, who shares his nomination with Siedah Garrett and Carlinhos Brown, says "Rio" director Carlos Saldanha delivered the good news to him.

"I don't know much about the voting process really. I'm not an expert in that, but I'm so happy about me being nominated," Mendes said Tuesday afternoon. "I don't really know the criteria, but I can only think about celebrating."

Winners of the 84th annual Academy Awards will be announced Feb. 26 in a ceremony that will air live on ABC from the Kodak Theatre in Hollywood.

____

Online:

http://oscar.go.com/

____

Mesfin Fekadu covers entertainment for The Associated Press. Follow him on Twitter at http://twitter.com/musicmesfin

Source: http://us.rd.yahoo.com/dailynews/rss/music/*http%3A//news.yahoo.com/s/ap/20120125/ap_en_mu/us_oscar_nominations_best_original_song

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Wednesday, January 25, 2012

Apple iPhone now more popular than all Android smartphones in US combined: report (Digital Trends)

iphone-4-vs-4s

In the US, Apple?s iPhone has surpassed the smartphone market share of all Android devices combined, according to new numbers out from research firm Kantar Worldpanel ComTech, as reported by Reuters. But the difference is almost invisible: Apple now owns 44.9 percent of the market; handsets running Google?s Android operating system now own just 44.8 percent.

Though the difference in popularity may be small, Apple?s growth is anything but. By Kantar?s count, Apple?s market share has doubled over the past year alone, while Android devices have fallen about 5 percent, from a high of 50 percent. Windows Phone devices now account for less than 2 percent, on average, across nine key world markets.

A recent study from Nielsen corroborates Kantar?s numbers. According to Nielsen, 44.5 percent of customers who purchased a smartphone during the last three months of 2012 bought an iPhone, and 57 percent of those buyers got the iPhone 4S, Apple?s newest handset. At that time, Android still remained the No. 1 smartphone category, with 46.9 percent of buyers going for a Google-powered device. ?

News of Apple?s new-found dominance in the US smartphone game follows the company?s latest quarterly earnings report, which showed record iPhone and iPad sales, and a record revenue of $46.3 billion. Apple sold 37.04 million iPhones during the quarter (which spanned the final three months of 2011), a 128 percent increase over the same period in 2010. And iPad sales jumped 111 percent year-over-year, to 15.43 million.

While Apple?s iPhone sales are staggering, it?s more surprising that the entire Android market put together is failing to beat back a single line of handsets ? even if they are Apple handsets. We would be surprised in Android doesn?t surge back into first place over the coming months, as more and more customers go for far faster 4G LTE-enabled devices, which the iPhone 4S is not.

This article was originally posted on Digital Trends

More from Digital Trends

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Worldwide smartphone sales rose 96 pct in summer 2010

Source: http://us.rd.yahoo.com/dailynews/rss/applecomputer/*http%3A//news.yahoo.com/s/digitaltrends/20120125/tc_digitaltrends/appleiphonenowmorepopularthanallandroidsmartphonesinuscombinedreport

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Love Life: California Academy of Sciences Photo Competition


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Image by Lennon Day-Reynolds, taken at the California Academy of Sciences for the Love Life 2012 photo competition (used under a CC-BY-NC 2.0 license)

One of my favorite institutions, the California Academy of Sciences in San Francisco, is holding a photography competition:

The Love Life photo competition returns for a second year with two new categories and many more prizes! Submit your loveliest photos of the California Academy of Sciences and the natural world for judging by top photo experts. Then vote for your favorite photos online to be entered in the People?s Choice Award. All winners will be announced at the March 1st Nightlife.

Most categories require photographs captured at the museum itself. One- for photography that encourages awareness of, or action for, the natural world- accepts submissions from anywhere.

The contest allows photographers to retain copyright, and the deadline is February 1st.

Love Life 2012 Competition

image source

Alex WildAbout the Author: Alex Wild is an Illinois-based entomologist who studies the evolutionary history of ants. In 2003 he founded a photography business as an aesthetic complement to his scientific work, and his natural history photographs appear in numerous museums, books, and media outlets. Follow on Twitter @myrmecos.

The views expressed are those of the author and are not necessarily those of Scientific American.

Source: http://rss.sciam.com/click.phdo?i=5dfdf05de22a18340bba82e3ff5eb5f8

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Tuesday, January 24, 2012

Putin foe could be barred from Russian election (Reuters)

MOSCOW (Reuters) ? Russian liberal opposition leader Grigory Yavlinsky could be barred from running against Vladimir Putin in a presidential election after officials said Monday there were problems with his registration as a candidate.

Opinion polls show Yavlinsky has no chance of winning the March 4 election but the refusal to let him run would be a slap in the face for leaders of protests by tens of thousands of demonstrators demanding fair elections and political reform.

Central Election Commission officials told Russian news agencies there were errors in about a quarter of the 2 million signatures of support Yavlinsky had submitted as a requirement to enter the election, much higher than the permitted amount.

A final decision on his candidacy is expected to be announced by the commission later this week or next.

Reducing the number of candidates could improve Putin's chances of winning the election in the first round, avoiding a run-off he would face if he does not receive at least 50 percent of the votes cast.

"This is a totally political decision," Yavlinsky, 59, told a news conference, a view shared by other opposition leaders and representatives of the Yabloko party he co-founded.

Yabloko leader Sergei Mitrokhin wrote in a blog: "Putin will decide this matter himself."

Mitrokhin suggested Putin did not want Yavlinsky to run because it could take votes from billionaire Mikhail Prokhorov, a liberal contender who he said was backed by Putin.

Mitrokhin also indicated that Yabloko representatives would be unable to monitor the election if Yavlinsky, who has twice run for president and lost, did not take part.

Election officials said Monday Prokhorov's candidacy had been confirmed after he submitted enough signatures.

PUTIN FACES CRITICISM

As independent candidates, Prokhorov and Yavlinsky had to collect 2 million signatures. Candidates from parties in parliament, such as Communist Gennady Zyuganov and nationalist Vladimir Zhirinovsky, did not have to meet this requirement.

Prokhorov, whose assets in an $18-billion business empire include the New Jersey Nets, has dismissed rivals' allegations that he is a Kremlin tool who has been allowed to run to split the opposition and give the election an air of legitimacy.

Putin, 59, was president for eight years from 2000 and ushered his ally, Dmitry Medvedev, into the post in 2008 because the constitution barred him from a third successive term. Putin became prime minister but remained Russia's dominant leader.

Opinion polls suggest Putin will easily win the election but his image has been dented by unusually large protests in Russia since a parliamentary election on December 4 which independent monitors say was slanted to favor his United Russia party.

Tens of thousands of people have taken part in protests since then, mainly in Moscow and St Petersburg, to demand the election be rerun, the election commission chief dismissed and more opposition parties registered.

Human Rights Watch, an international rights monitor, said in its annual report released Sunday that Putin's decision to run for a six-year, third term as president cast a shadow over prospects for political reforms.

It also said pro-government parties had benefited from "disproportionate access to media and abuse of administrative resources."

(Editing by Janet Lawrence)

Source: http://us.rd.yahoo.com/dailynews/rss/russia/*http%3A//news.yahoo.com/s/nm/20120123/ts_nm/us_russia_yavlinsky

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Seal "Shocked" By Heidi Klum Divorce


Mere hours after Heidi Klum and Seal confirmed their divorce, interviews between Seal and Ellen DeGeneres (airing today) and PBS' Tavis Smiley (Friday) hit the web.

The topic of his separation was not off the table. Not even close.

About to embark on a new album tour, Seal is more than willing to openly speak about what shocked us - and himself, apparently. "I think we were shocked," he said.

"You go into these things with the greatest intentions when you say 'I do' and you say ''Till death do us part.' Those vows hold value," the singer told Ellen.

"They are not just words. These things happen. We pretty much said how we feel and made it clear in the release statement."

"But, for intents and purposes of this show, you just grow apart after awhile. You try and you work through it and the thing that you quickly realize when you are married and you become a parent is you do the best that you can."

"It makes you actually appreciate your parents a lot more."

"The thing that I'm most proud about this great woman who married - and I really do mean that from the bottom of my heart - is that together she has given me four incredible gifts, four beautiful children. 

"She still, in my opinion, the most wonderful woman in the world."

"I think our priority was to remain civil and do this thing with dignity. We still very much love each other. It's not a question of we were never to follow suit of some breakup or separations that you hear about, especially in our industry."

"It's a shame. To say that neither of us were grieving would be an out and out lie, and I don't mind telling you that. We both have a tremendous amount of respect and love and we try and do this with as much dignity as we possibly can."

"And of course, when you have four children, you hope and pray that the rest of the world will respect that we have four children and that their little hearts are at stake, too."

Here's Seal on Tavis Smiley's show as well:

Source: http://www.thehollywoodgossip.com/2012/01/seal-shocked-by-heidi-klum-divorce/

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Monday, January 23, 2012

Analysis: Rivals to "The Artist" are down to their last shot (Reuters)

PARK CITY, Utah, Jan 22 (TheWrap.com) ? One more chance.

That's all that remains for the films hoping to throw a roadblock in the way of the inexorable march to the Oscar stage by "The Artist."

When Michel Hazanavicius' black-and-white silent film won the top award from the Producers Guild on Saturday night, it silenced the last nagging notion that the charming film might be too slight to win Oscar's Best Picture award.

Now that the producers have voted it the year's best, on ballots that were tallied using the same system that the Academy uses, it's all but inevitable that Oscar voters will do the same.

The only obstacle that remains is next Saturday's Directors Guild of America Awards, where Hazanavicius will be competing against Woody Allen ("Midnight in Paris"), David Fincher ("The Girl With the Dragon Tattoo"), Alexander Payne ("The Descendants") and Martin Scorsese ("Hugo").

That's a quartet of directors with far more experience in the United States, and far more ties to the other directors, assistant directors, stage managers and directorial team members who make up the DGA.

In that company, the little-known Frenchman seems like an uneasy favorite. But then, Tom Hooper was in the same position last year with "The King's Speech," and he won -- essentially because voters liked his movie better than the other guys' movies, the same way they seem to like "The Artist" better.

But the DGA does offer the possibility of an intriguing scenario, particularly if Scorsese or Payne wins.

In that case, the win could create a clear No. 2, an alternative to "The Artist" for Oscar voters to rally around. And maybe, just maybe, the film's curious aura of inevitability could start to fade.

But for that to happen, either "The Descendants" or "Hugo" would have to establish itself as the alternative. "The Descendants" has come closer than "Hugo" to doing that so far, and it has an outside chance to actually establish a little momentum with a DGA win, a SAG ensemble victory and a Writers Guild Award (for which "The Artist" is ineligible).

But it has to start with the DGA, or the game really will be over.

The tricky thing is that the guy who's the master of the "we're No. 2" strategy, Harvey Weinstein, is the guy who doesn't need to use it this year, because his film is No. 1.

Weinstein began using the strategy when he ran Miramax Films back in 1994, and managed to position a movie that was way too daring for the conservative academy, Quentin Tarantino's "Pulp Fiction," as the chief rival to frontrunner (and eventual winner) "Forrest Gump."

And he did it again and again over the next decade. When "Saving Private Ryan" was the frontrunner in 1998, Miramax kept pushing "Shakespeare in Love," making it the movie of choice for everybody who couldn't quite endorse the war movie -- which, in the end, was enough to give "Shakespeare," and Harvey, a Best Picture victory.

When "American Beauty" had all the momentum but seemed awfully dark and adventurous for the more conservative side of the Academy, Miramax pulled out all the stops to position "The Cider House Rules" as the safer alternative, even if that meant misrepresenting a film whose hero was a drug-addicted doctor who performed abortions.

And when the battle seemed to be between "The Hurt Locker" and "Avatar" two years ago, Weinstein began trumpeting how his film, "Inglourious Basterds," was actually the one that could pull off the upset.

The strategy doesn't usually work. (It didn't for "Pulp Fiction," "The Cider House Rules" or "Inglourious Basterds.") But when you're dealing with a frontrunner like "The Artist," somebody needs to persuade voters that if you can't fully endorse the silent flick, there's only one real alternative.

And the fact that nobody has done that is one of the main reasons why "The Artist" now seems all but preordained as a winner.

Source: http://us.rd.yahoo.com/dailynews/rss/celebrity/*http%3A//news.yahoo.com/s/nm/20120122/film_nm/us_theartist_oscars

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Sharon Stone for the 1st Time on Brain Hemorrhage, Miscarriages and Messy Divorce

For the first time ever, Sharon Stone speaks candidly about a decade of personal struggle, from the brain hemorrhage that nearly killed her to coping with miscarriages and her painful divorce and custody battle with Phil Bronstein. From this, Stone has emerged a devoted mother and philanthropist. She tells AARP The Magazine, ?I?ve made humanitarian [...]

Source: http://www.celebritymound.com/sharon-stone-for-the-1st-time-on-brain-hemorrhage-miscarriages-and-messy-divorce/?utm_source=rss&utm_medium=rss&utm_campaign=sharon-stone-for-the-1st-time-on-brain-hemorrhage-miscarriages-and-messy-divorce

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Sunday, January 22, 2012

Asthma Meds Likely Safe During Pregnancy: Study (HealthDay)

FRIDAY, Jan. 20 (HealthDay News) -- A new study found no statistically significant link between asthma medication use during pregnancy and common birth defects.

However, the study did find a positive association between some rare birth defects and mothers with asthma, and potentially with their medication use. But, the researchers couldn't tease out whether the problem was a loss of oxygen from less than well-controlled asthma or an effect of medications.

"Worsening asthma is a risk to the mom and the fetus. Hypoxia (a lack of oxygen) we know is a problem for a developing fetus. And, the potential risk they found here is very small. Even if it turns out to be a true increase, the risk is so small. This study raises more questions than it answers," said Dr. Natalie Meirowitz, chief of the division of maternal fetal medicine at Long Island Jewish Medical Center in New Hyde Park, N.Y.

What's most important, she said, is that expectant mothers with asthma don't just stop their medications. "That's really a problem, and then they end up needing more medication," she said.

Findings from the study were published online Jan. 16, ahead of February print publication in Pediatrics.

Between 4 percent and 12 percent of expectant mothers have asthma, according to background information in the article. Current guidelines recommend that women keep taking their asthma medications during pregnancy.

There are two main types of asthma medications: bronchodilators (also known as rescue medication) and anti-inflammatories, which include inhaled and oral steroids, as well as several other medications. Anti-inflammatory medications are generally used long term to help control asthma symptoms.

For the study, the researchers compared nearly 2,900 infants born with birth defects to more than 6,700 babies born with no birth defects. Mothers of these infants were asked to recall their medication use one month before and during pregnancy.

For most birth defects, the researchers found no statistically significant associations between asthma medication use and the development of birth defects.

They did, however, find a positive association between asthma medication use and certain rare birth defects. The risk of isolated esophageal atresia -- an abnormality of the esophagus -- was more than doubled in women who used bronchodilators. The risk of isolated anorectal atresia -- a malformed anus -- was more than doubled with maternal anti-inflammatory use. And, the risk of omphalocele -- a defect in the abdominal wall -- was more than quadrupled for either type of asthma medication.

But, the authors wrote, the "observed associations may be chance findings or may be the result of maternal asthma severity and related hypoxia rather than the medication use."

They added that it's also important to keep these findings in context. The rate of these birth defects ranged from 1.2 to 4.6 per 10,000 births. So, even a four-fold increase in the risk of having one of these defects results in far less than a 1 percent chance for any individual woman and her child.

"As obstetricians, we need to pay attention to this, but it's really important to oxygenate mom. We really need to make sure that there's oxygen flowing freely between mom and baby," said Dr. Mary Rosser, an obstetrician with Montefiore Medical Center in New York City.

Also, Rosser pointed out that there was a lot that wasn't known about the expectant mothers. The authors weren't able to assess the severity of their asthma. They also didn't know anything about the medication doses.

Asthma expert Dr. Jennifer Appleyard agreed with Rosser and Meirowitz. "They really couldn't tease apart what was the medicine and what was the asthma," she said.

"You need to treat the asthma. There's more risk to uncontrolled asthma than a slight possible risk of a rare birth defect," said Appleyard, the chief of allergy and immunology at St. John Hospital and Medical Center in Detroit.

"No matter what type of patient you're treating -- expectant mom or not -- the goal is to treat patients with the minimum amount of medication necessary," she added.

Rosser and Meirowitz said that, ideally, women should visit their obstetrician/gynecologist before getting pregnant to review their medication use and to make sure that their asthma is well controlled.

More information

Learn more about asthma during pregnancy from the American College of Allergy, Asthma and Immunology.

Source: http://us.rd.yahoo.com/dailynews/rss/diseases/*http%3A//news.yahoo.com/s/hsn/20120120/hl_hsn/asthmamedslikelysafeduringpregnancystudy

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Obama's State of the Union: Jobs, re-election time

President Barack Obama sings before speaking at a campaign event, Thursday, Jan. 19, 2012, at the Apollo Theatre in the Harlem neighborhood of New York. (AP Photo/Haraz N. Ghanbari)

President Barack Obama sings before speaking at a campaign event, Thursday, Jan. 19, 2012, at the Apollo Theatre in the Harlem neighborhood of New York. (AP Photo/Haraz N. Ghanbari)

President Barack Obama pauses before shaking hands at a campaign event, Thursday, Jan. 19, 2012, at the Apollo Theatre in the Harlem neighborhood of New York. (AP Photo/Haraz N. Ghanbari)

President Barack Obama speaks at a campaign event, Thursday, Jan. 19, 2012, at the Apollo Theatre in the Harlem neighborhood of New York. (AP Photo/Haraz N. Ghanbari)

(AP) ? Vilified by the Republicans who want his job, President Barack Obama will stand before the nation Tuesday night determined to frame the election-year debate on his terms, using his State of the Union address to outline a lasting economic recovery that will "work for everyone, not just a wealthy few."

As his most powerful chance to make a case for a second term, the prime-time speech carries enormous political stakes for the Democratic incumbent who presides over a country divided about his performance and pessimistic about the nation's direction. He will try to offer a stark contrast with his opponents by offering a vision of fairness and opportunity for everyone.

In a preview Saturday, Obama said in a video to supporters that the speech will be an economic blueprint built around manufacturing, energy, education and American values.

He is expected to announce ideas to make college more affordable and to address the housing crisis still hampering the economy three years into his term, people familiar with the speech said. Obama will also propose fresh ideas to ensure that the wealthy pay more in taxes, reiterating what he considers a matter of basic fairness, the officials said.

His policy proposals will be less important than what Obama hopes they all add up to: a narrative of renewed American security with him at the center, leading the fight.

"We can go in two directions," Obama said in the campaign video. "One is toward less opportunity and less fairness. Or we can fight for where I think we need to go: building an economy that works for everyone, not just a wealthy few."

That line of argument is intended to tap directly into concerns of voters who think America has become a nation of income inequality, with rules rigged to help the rich. The degree to which Obama or his eventual Republican opponent can better connect with millions of hurting Americans is expected to determine November's presidential election.

Obama released his video hours ahead of the South Carolina primary, where Republican candidates fought in the latest fierce contest to become his general election rival.

The White House knows Obama is about to get his own stage to outline a re-election vision, but carefully. The speech is supposed to an American moment, not a campaign event.

Obama didn't mention national security or foreign policy in his preview, and he is not expected to break ground on either one in his speech.

He will focus on the economy and is expected to promote unfinished parts of his jobs plan, including the extension of a payroll tax cut that is soon to expire.

Whatever Obama proposes is likely to face long odds in a deeply divided Congress.

More people than not disapprove of Obama's handling of the economy, and he is showing real vulnerability among the independent voters who could swing the election. Yet he will step into the moment just as the economy is showing life. The unemployment rate is still at a troubling 8.5 percent, but at its lowest rate in nearly three years. Consumer confidence is up.

By giving a sneak peek to millions of supporters on his email list, Obama played to his Democratic base and sought to generate an even larger audience for Tuesday's address. He is unlikely to getter a bigger stage all year.

More people watched last year's State of the Union than tuned in to see Obama accept the Democratic presidential nomination in Denver in 2008.

The foundation of Obama's speech is the one he gave in Kansas last month, when he declared that the middle class was at a make-or-break moment and he railed against "you're on your own" economics of the Republican Party. His theme then was about a government that ensures people get a fair shot to succeed.

The State of the Union will be the details to back that up.

But even so, the speech will still be a framework ? part governing, part inspiration.

The details will be rolled out in full over the next several weeks, as part of Obama's next budget proposal and during his travels, which will allow him more media coverage.

On national security, Obama will ask the nation to reflect with him on a momentous year of change, including the end of the war in Iraq, the killing of al-Qaida terrorist leader Osama bin Laden and the Arab Spring protests, with people clamoring for freedom. He is expected to note the troubles posed by Iran and Syria without offering new positions about them.

Despite low expectations for legislation this year, Obama will offer short-term ideas that would require action from Congress. For now, the main looming to-do item is an extension of a payroll tax cut and unemployment benefits, both due to expire by March.

His travel schedule following his speech, to politically important regions, offers clues to the policies he was expected to unveil.

Both Phoenix and Las Vegas have been hard hit by foreclosures. Denver is where Obama outlined ways of helping college students deal with school loan debt. Cedar Rapids, Iowa, and Detroit are home to a number of manufacturers. And Michigan was a major beneficiary of the president's decision to intervene to rescue the American auto industry.

Republican leaders in Congress say Obama has made the chances of cooperation even dimmer just over the last several days. He enraged Republicans by installing a consumer watchdog chief by going around the Senate, which had blocked him, and then rejected a major oil pipeline project the GOP has embraced.

Obama is likely, once again, to offer ways in which a broken Washington must work together. Yet that theme seems but a dream given the gridlock he has been unable to change.

The address remains an old-fashioned moment of national attention; 43 million people watched it on TV last year. The White House website will offer a live stream of the speech, promising extra wrinkles for people who watch it there, and then invite people to send in questions to administration officials through social media such as Twitter and Facebook.

Obama's campaign is also organizing and promoting parties around the nation for people to watch the speech.

__

AP deputy director of polling Jennifer Agiesta and Associated Press writer Ken Thomas contributed to this report.

__

Online:

White House: http://www.whitehouse.gov

___

Follow Ben Feller at http://twitter.com/BenFellerDC

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2012-01-21-US-Obama-State-of-the-Union/id-9e76772ecfda4f1f98a4521a7392509a

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Saturday, January 21, 2012

Video: Ron Paul Gives Speech on Civil War in Front of Giant Confederate Flag (Little green footballs)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories Stories, News Feeds and News via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/189125998?client_source=feed&format=rss

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Roche melanoma pill spurs growth of less harmful cancers (Reuters)

CHICAGO (Reuters) ? A new study helps explain why up to a third of advanced melanoma patients who take Roche Holding's pill Zelboraf develop a less deadly form of skin cancer known as cutaneous squamous cell carcinoma, and even points to a potential fix.

They said combining drugs like Zelboraf, which block a mutation known as BRAF, with a second melanoma drug that blocks a different mutation known as MEK helped to solve this problem in lab mice.

GlaxoSmithKline has already shown early promise in a trial combining drugs that block both MEK and BRAF, and the study shows why this duo may be more effective and have fewer side effects than drugs that target either mutation separately.

Both MEK and BRAF are mutations in the same pathway are used by the cancer to drive tumor growth.

"The combination of BRAF and the MEK inhibitors gives you a better response, and also prevents the emergence of these secondary tumors," said Professor Richard Marais of the Institute of Cancer Research in London, whose study appears in the New England Journal of Medicine.

About 50 percent of patients who get melanoma have the BRAF mutation and can be treated with vemurafenib. But doctors noticed that many of these patients developed another type of skin cancer called cutaneous squamous cell carcinoma, which had to be removed surgically.

To understand why, the team -- which included researchers from the University of California Los Angeles, Roche and Daiichi Sankyo's Plexxikon -- studied squamous cell cancer tissue from 21 malignant melanoma patients who had been treated with vemurafenib in a clinical trial.

They found about 60 percent also had RAS mutations, likely caused by sun exposure, that could predispose them to squamous cell cancer. And unlike melanoma cells, when these mutated cells became exposed to a BRAF inhibitor, they tend to grow.

"It's not that these drugs (BRAF inhibitors) are tumor promoters. What they do is accelerate growth of preexisting but asymptomatic tumors in the skin of patients who are susceptible to that disease," he said.

Treatment with a MEK inhibitor blocks this side effect, Marais said.

Tests in lab mice found that those with both types of skin cancers who were treated with a combination of a BRAF and MEK drug had fewer lesions.

And there are hints that process may work in people.

In June, GSK presented the first data from its combination BRAF and MEK inhibitors at the American Society of Clinical Oncology meeting in June.

"One of the things they found is the patients had fewer skin lesions. It actually works in people," Marias said.

He said the findings may spur more companies to combine their BRAF and MEK inhibitors.

"Not only will it give you the best response but it won't give you the secondary events," he said.

Melanoma globally afflicts nearly 160,000 new people each year. It can spread quickly to internal organs and average survival is six to nine months.

Zelboraf was developed in partnership with Daiichi Sankyo and is the second drug to be approved for melanoma in recent months. Prior to 2011, the FDA had not approved a new melanoma drug in 13 years.

(Reporting By Julie Steenhuysen; Editing by Eric Walsh)

Source: http://us.rd.yahoo.com/dailynews/rss/cancer/*http%3A//news.yahoo.com/s/nm/20120119/hl_nm/us_cancer_melanoma_drugs

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